Listar por autor "Carballo-Pedrares, Natalia"

Mostrando ítems 1-6 de 6

    • Chondrogenic differentiation of human mesenchymal stem cells via SOX9 delivery in cationic niosomes 

      Carballo-Pedrares, Natalia; Sanjurjo-Rodríguez, Clara; Señarís, José; Díaz-Prado, Silvia; Rey-Rico, Ana (MDPI, 2022-10-28)
      [Abstract] Gene transfer to mesenchymal stem cells constitutes a powerful approach to promote their differentiation into the appropriate cartilage phenotype. Although viral vectors represent gold standard vehicles, because ...

    • Development of new non-viral systems for genetic modification of senescent cells 

      López-Seijas, Junquera; Miranda-Balbuena, Diego; Iglesias-Fente, Alba; Sacristán-Santos, Marta; Carballo-Pedrares, Natalia; Arufe, M.C.; Rey-Rico, Ana; Fafián Labora, Juan Antonio (Cell Press, 2023-03-20)
      [Abstract] Senescence is a process characterized by a prolonged irreversible cell-cycle arrest. The accumulation of senescent cells in tissues is related to aging and to the development of age-related diseases. Recently, ...

    • Gene-activated cryogels for cartilage repair 

      Carballo-Pedrares, Natalia (2023)
      [Abstract] The increase in life expectancy associated with developments in the field of medicine has prompted the prevalence of degenerative diseases related to aging. Specifically, articular cartilage is a tissue with a ...

    • Hydrogel-based localized nonviral gene delivery in regenerative medicine approaches: an overview 

      Carballo-Pedrares, Natalia; Fuentes Boquete, Isaac Manuel; Díaz-Prado, Silvia; Rey-Rico, Ana (MDPI, 2020-08-10)
      [Abstract] Hydrogel-based nonviral gene delivery constitutes a powerful strategy in various regenerative medicine scenarios, as those concerning the treatment of musculoskeletal, cardiovascular, or neural tissues disorders ...

    • Niosomes-Based Gene Delivery Systems for Effective Transfection of Human Mesenchymal Stem Cells 

      Carballo-Pedrares, Natalia; Kattar, Axel; Concheiro, Ángel; Álvarez-Lorenzo, Carmen; Rey-Rico, Ana (Elsevier, 2021-07-11)
      [Abstract] Gene transfer to mesenchymal stem cells (MSCs) has arisen as a powerful approach to increase the therapeutic potential of this effective cell population. Over recent years, niosomes have emerged as self-assembled ...

    • Scaffold-Mediated Gene Delivery for Osteochondral Repair 

      Madry, Henning; Venkatesan, Jagadeesh Kumar; Carballo-Pedrares, Natalia; Rey-Rico, Ana; Cucchiarini, Magali (MDPI, 2020-09-29)
      [Abstract] Osteochondral defects involve both the articular cartilage and the underlying subchondral bone. If left untreated, they may lead to osteoarthritis. Advanced biomaterial-guided delivery of gene vectors has ...